INNOVATIVE THERAPEUTIC STRATEGIES FOR MANAGING POST CASTRATION SYNDROME AFTER OVARIAN HYPERSTIMULATION
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INNOVATIVE THERAPEUTIC STRATEGIES FOR MANAGING POST CASTRATION SYNDROME AFTER OVARIAN HYPERSTIMULATION. (2025). MEDICINE, PEDAGOGY AND TECHNOLOGY: THEORY AND PRACTICE, 3(6), 60-62. https://universalpublishings.com/~niverta1/index.php/mpttp/article/view/12285

Abstract

Definition and clinical importance Post‑castration syndrome (PCS) can develop after oocyte retrieval and luteal phase; severe ovarian hyperstimulation syndrome (OHSS) manifests as ascites, electrolyte imbalance, ovarian enlargement, and systemic signs. Although PCS is relatively rare, complications can be life-threatening and compromise IVF outcomes.

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References

1. Lainas TG et al.: Outpatient GnRH antagonist for established PCS resolves hematologic and ascitic findings within 7 days pubmed.ncbi.nlm.nih.gov.

2. Orvieto et al.: GnRH agonist trigger + freeze-all eliminates OHSS risk in antagonist cycles with ≥18 follicles pubmed.ncbi.nlm.nih.gov.

3. Cochrane reviews/meta-analyses: Cabergoline prophylaxis reduces OHSS incidence via VEGF modulation en.wikipedia.org.

4. De Vos et al.: In vitro maturation offers safer ART for PCOS with similar success rates en.wikipedia.org.

5. Wu et al.: AI model (“ILETIA”) enhances timing precision in stimulation, reducing risk factors .