Open Access · Peer Reviewed
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Keywords

Vitiligo,
alopecia areata,
psoriasis vulgaris,
Janus Kinase inhibitors,

How to Cite

JAK INHIBITORS AND TYK-2 INHIBITORS IN DERMATOLOGY (LITERATURE REVIEW). (2026). "XXI ASRDA INNOVATSION TEXNOLOGIYALAR, FAN VA TAʼLIM TARAQQIYOTIDAGI DOLZARB MUAMMOLAR" Nomli Respublika Ilmiy-Amaliy Konferensiyasi, 4(7), 6-18. https://universalpublishings.com/index.php/itfttdm/article/view/20410

Abstract

Monitoring and safety recommendations for primary care clinicians regarding  Janus  kinase  (JAK)  and  tyrosine  kinase  2  (TYK2)  inhibitors  in  inflammatory  skin  disorders  remain  insufficiently  defined  [1,  2].  This  review  summarizes  clinically 
relevant and updated guidance on the monitoring, efficacy, and safety profiles of these  agents.  A  systematic  review  of  PubMed  and  U.S.  

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DOI

References

1. Beard A. JAK 1-3 Inhibitors and TYK-2 Inhibitors in Dermatology. J Dermatol Clin Res. 2024. https://pmc.ncbi.nlm.nih.gov/articles/PMC11610805/

2. Martin G. A Review of Tyrosine Kinase 2 Inhibitors. Dermatol Ther (Heidelb). 2023. https://link.springer.com/article/10.1007/s13555-022-00878-9

3. Zheng Y, Han Y, Chen J, et al. Comparative efficacy and safety of JAK/TYK2 inhibitors and other oral drugs for moderate-to-severe plaque psoriasis: a systematic review and network meta-analysis. Indian J Dermatol Venereol

Leprol. 2024; 90: 590–598. https://ijdvl.com/comparative-efficacy-and-safety-of-jak-tyk2-inhibitors

4. Miot H A. JAK-STAT Pathway Inhibitors in Dermatology. J Dermatol Sci. 2023.

https://www.sciencedirect.com/science/article/pii/S0365059623001149

5. Ryguła I, Pikiewicz W, Kaminiów K. Novel Janus Kinase Inhibitors in the

Treatment of Dermatologic Conditions. Molecules. 2023; 28(24): 8064.

https://www.mdpi.com/1420-3049/28/24/8064

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