Keywords
How to Cite
Abstract
From modern perspectives, peptic ulcer disease is considered a multifactorial poly-etiological disease. The founder of the neurogenic concept of lesion development, G. Bergman, believed that the main role in the pathogenesis is played by functional disorders of the autonomic nervous system with the predominance of the vagus nerve tone. Disruption of the harmonious effect on the stomach of parasympathetic and sympathetic parts of the autonomic nervous system leads to the formation of ulcers. The disruption of the sympathetic innervation of the gastroduodenal complex plays a significant role in the development of morpho- functional changes. The flow of sympathetic pulses causes excessive excretion of catecholamines, leading to disruption of tissue trophic processes. Stress stimulates the function of the hypothalamus. This causes hypersecretion of hydrochloric acid and pepsin, hypermotorism and hypertonia of the stomach, spasm of the blood vessels and ischemia.
References
1. B.Kadirov, F. Xamrabayeva. Helicobacter pylori and peptic ulcer disease, as well as views on eradication therapy//New day in medicine. – 2022. – V 1, No. 39. – P. 195–200.
2. KB Saidovich. Autonomic dystonia syndrome as one of the etiofactors in the development of peptic ulcer// Journal of Universal Science Research. - 2023 Volume 1, No.12. – P.810-818.
3. KB Saidovich. The State of the Autonomic Nervous System in Patients Suffering From Peptic Ulcer Autonomic Dystonia// International journal of health systems and medical sciences. - 2023. – Vol. 2 No. 5. – P289-292.
4. Khamrabaeva Feruza Ibragimovna, Kadirov Bekhruzbek Saidovich. Вегетативные расстройства и её роль в развитии язвенной болезни желудка и двенадцатиперстной кишки//Проблемы биологии и медицины. – 2021. No. 3 (136). P – 239-243.
5. Abdullayev RB, Makhmudova LI Features of Chemical Elements in Various Forms of Irritable Bowel Syndrome // Annals of RSCB, ISSN:1583-6258, Vol. 25, Issue 2, 2021, Pages. 2993 - 3000.
6. Makhmudova LI, Akhmedova N.Sh., Ergashov BB Clinical manifestation of irritable bowel syndrome. Art of medicine. International medical scientific journal. Vol. 1, Issue 2. 2021:24-33.
7. KB Saidovich. Probiotics and their role in inflammatory diseases of the intestinal tract//Thematics Journal of Microbiology. – 2023. -V 7, No 1. 8. KB Saidovich. Clinical features of autonomic disorders in gastric and duodenal ulcers//Barqarorlik va yetakchi tadqiqotlar.- 2023. V 3, No 12. – P. 352-357.
9. KB Saidovich. State of the psychoemotional sphere in patients with peptic ulcer of the stomach and duodenum// European journal of modern medicine and practice. – 2023. – V 3, No 12. – P. 248-254.
10. Волкова Т.А., Захарченко Д.И., Влияние типа вегетативного реагирования на характер гастродуоденальной патологии // Вопросы педиатрии. – Ярославль, 2015. – С. 74.
11. Григорьев П.Я., Яковенко Э.П. Клиническая гастроэнтерология // М.: МИА., 2011. – 647 с.
12. Гриневич В.Б., Успенский Ю.П., Шабанова Г.Ж. Особенности язвенной болезни, не связанной с Helicobacter pylori // Тер. архив. – 2012. – № 2. – С. 24-27.
13.Лазебник Л.Б., Арбузова В.Г., Соколова Г.Н. Роль стресса в этиопатогенезе язвенной болезни двенадцатиперстной кишки у больных молодого возраста // Экспериментальная и клиническая гастроэнтерология. – 2012. – № 4. – С. 30-33.
14. Мальцев С.В., Волгина С.Я. Особенности психовегетативного состояния при хроническом гастродуодените у детей старшего возраста // Педиатрия. – 2016. – № 4. – С. 38-42.
15. Менделевич В.Д. Клиническая и медицинская психология – М.: Медпресс, 2010. – 592 с.
This work is licensed under a Creative Commons Attribution 4.0 International License.