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Abstract
Sex-based pharmacology examines how biological sex can influence the way medicines are absorbed, distributed, metabolized, eliminated, and experienced by the body. Differences in body composition, hormones, organ function, gene expression, transport proteins, and immune responses may alter drug exposure, therapeutic benefit, or the risk of adverse effects. These differences are not universal: the direction and clinical importance depend on the medicine, dose, age, health status, and individual patient.
References
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