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Keywords

gut–brain axis; microbiota–gut–brain axis; eating behaviour; appetite; satiety; gut hormones; GLP-1; ghrelin; PYY; vagus nerve; food reward; nutrition.

How to Cite

GUT–BRAIN AXIS: A NEW PERSPECTIVE ON EATING BEHAVIOUR. (2026). SYNAPSES: INSIGHTS ACROSS THE DISCIPLINES, 3(10), 174-181. https://universalpublishings.com/index.php/siad/article/view/21066

Abstract

Eating is often described as a simple response to hunger, but everyday food choices are  shaped by a much richer conversation between the gastrointestinal tract and the brain.  The  gut–brain  axis  integrates  mechanical  distension,  nutrients,  gut  hormones,  microbial metabolites, vagal signals and central reward pathways to influence hunger,  satiation, satiety and food preference. This narrative review presents a human-centred  view of how that communication may help explain why people sometimes eat when 
they are not physiologically hungry, stop eating before energy needs are fully restored,  or find highly palatable foods unusually difficult to resist. 

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References

1. Clarke GS, Page AJ, Eldeghaidy S. The gut–brain axis in appetite, satiety, food intake, and eating behavior: insights from animal models and human studies. Pharmacol Res Perspect. 2024;12(5):e70027. doi:10.1002/prp2.70027.

2. Hong S-H, Choi K-M. Gut hormones and appetite regulation. Curr Opin Endocrinol Diabetes Obes. 2024;31(3):115–121. doi:10.1097/MED.0000000000000859.

3. Holt MK, et al. The impact of gut hormones on the neural circuit of appetite and satiety: a systematic review. Neurosci Biobehav Rev. 2017;80:80–91.

4. Yu M, Yu B, Chen D. The effects of gut microbiota on appetite regulation and the underlying mechanisms. Gut Microbes. 2024;16(1):2414796. doi:10.1080/19490976.2024.2414796.

5. The gut microbiome and eating behavior outcomes: a systematic review. Nutr Rev. 2025. PMID:39667924.

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