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Abstract
The article provides a detailed analysis of the pathogenesis underlying intestinal microbiota transformation in post-cholecystectomy patients. The role of gallbladder reservoir function loss, continuous bile acid influx into the duodenum, and accelerated enterohepatic circulation is thoroughly reviewed. Key taxonomic shifts at the phylum and genus levels, as well as the mechanisms behind the accumulation of cytotoxic secondary bile acids, are described. Modern therapeutic strategies for correcting post-cholecystectomy dysbiosis, including dietary modifications, synbiotics, and targeted pharmacotherapy, are highlighted.
References
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