Keywords
o‘pka kasalliklari
sarkoidoz
fibrozlanuvchi
alveolit
How to Cite
Abstract
Maqolada o‘pkaning interstitsial kasalliklari guruhida ko‘p uchraydigan va klinik-amaliy ahamiyatga ega bo‘lgan ikki holat - sarkoidoz hamda fibrozlanuvchi alveolitning zamonaviy tashxislash va davolash tamoyillari tahlil qilindi. Interstitsial kasalliklar alveola devori, interstitsium, kapillyar tarmoq va terminal bronxiolalar darajasida yallig‘lanish hamda fibroz bilan kechadi. Sarkoidozda asosiy morfologik belgi nekrozsiz granulomalar bo‘lsa, fibrozlanuvchi alveolitda progressiv chandiqlanish, o‘pka elastikligining pasayishi va gaz almashinuvining buzilishi ustun turadi. Maqolada klinik belgilar, HRKT, rentgenografiya, tashqi nafas funksiyasi, DLCO, bronxoalveolyar lavaj va biopsiya natijalarini kompleks baholash zarurligi asoslandi. Davolashda sarkoidoz uchun kuzatuv, glyukokortikoidlar va steroidni tejovchi immunosupressiv vositalar; fibrozlanuvchi alveolit/IPF uchun antifibrotik terapiya, kislorod, reabilitatsiya va transplantatsiya bo‘yicha yo‘naltirish mezonlari ko‘rsatildiReferences
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