Abstract
This literature review explores the pathomorphological changes in the adrenal glands of newborns with respiratory distress syndrome (RDS). The study focuses on the impact of hypoxia, hormonal imbalances, and stress responses on adrenal gland structure and function. Key findings include adrenal hypertrophy, degenerative changes (such as fatty and hydropic degeneration), impaired microcirculation, and necrotic changes in severe cases. The review highlights the role of cortisol and aldosterone deficiency in exacerbating RDS and emphasizes the need for further research into the mechanisms of adrenal insufficiency
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