Abstract
Questions related to the topic of the joint course of the new coronavirus infection COVID-19 and chronic obstructive pulmonary disease (COPD) are currently very relevant. This is due to the similarity of clinical manifestations, the complexity of diagnosis. COPD patients with comorbid diseases infected with SARS-CoV-2 represent a particularly vulnerable group of people with a complicated course and often an unfavorable outcome of the disease. In light of the above, the study of laboratory indicatorsfeatures of the course and risk factors for cardiovascular complications, the development of effective methods for the treatment and rehabilitation of patients with COPD in combination with the metabolic syndrome against the background of COVID-19 remains an urgent problem. A new effective approach has been developed for the early diagnosis of chronic obstructive pulmonary disease (COPD) based on the clinical and immunological characteristics of the disease. The study included 46 patients with COPD who were in the departments of allergology and pulmonology of the Samarkand city medical association in 2022-2023. Changes in the profile of interleukins in blood serum depending on the stage and sex in COPD are described in detail.
References
Berdikulovna, Kholzhigitova Mukhayo. "The state of changes in theImmune system in patients with Сhronic Obstructive Bronchitisand the effect of immunotherapy on the dynamics of immunological parameters." Journal of Critical Reviews. Issn-2394-5125 7.14 (2020).
Холжигитова, М. Б., et al. "Характеристика Клинико-Функциональных Показателей У Больных Covid-19 На Фоне Хронической Обструктивной Болезни Легких." Journal of Science in Medicine and Life 1.2 (2023): 106-111.
Kholzhigitova M. B., Ubaidullaeva N. N. Features of the course of sleep apnea syndrome in patients with chronic obstructive pulmonary disease. Journal of Cardiorespiratory Research. Volume 3 No. 4. 2022. http://dx.doi.org/10.5281/zenodo.7366224 pp. 83-86.
Kholzhiitova M. B., Ubaydullaeva N. N. Common characteristics of obese patients with chronic obstructive pulmonary disease include the presence of metabolic syndrome. Oriental journal of medicine and pharmacology doi: https://doi.org/10.37547/supsci-ojmp-02-06-03 21-29.
Kholzhiitova M. B., Ubaydullaeva N. N. Changes in functional parameters and exercise tolerance in patients with chronic obstructive pulmonary disease.Oriental journal of biology and chemistry sjif 2021-5. 76, 2022-5. 799. P 14-18. Doi: https://doi.org/10.37547/supsci-ojbc-02-03-03.
Kholzhigitova M. B., Tashmetov Kh. M., Ubaydullaeva N.N. Tobacco addiction in young people, ways of optimization and prevention. Samarkand State Medical Institute. Journal of Cardiorespiratory Research No. 1.1 (2022) doi http://dx.doi.org/10.26739/2181-0974-2022-1page 67
Kholzhigitova M.B., Okboev T.A. Samarkand State Medical Institute. Journal of Cardiorespiratory Research. Assessing the significance of genetic research in the early diagnosis of bronchial asthma in the family. No. 2.1 (2022) doi http://dx.doi.org/10.26739/2181-0974-2022-2.1str 268.
Kholzhigitova Mukhayo Berdikulovna.The state of changes in the Immune system in patients with Сhronic Obstructive Bronchitisand the effect of immunotherapy on the dynamics of immunological parameters. Journal of Critical Reviews. Issn-2394-5125. Vol 7, issue 14, 2020.
Kholzhigitova M.B., Safarova M.P. Endoscopic signs in the mucosa depending on the severity of the course in chronic obstructive pulmonary disease. THE Thematics Journal of Education. Impact factor (UIF) 7.47 ISSN 2249-9822.2022. Pag 35-45.2022.
Kholzhigitova M.B., Safarova M.P. Features of the course of sleep apnea syndrome in patients with chronic obstructive pulmonary disease. ENVIRONMENTAL HEALTH RESEARCH. Impact factor (UIF) 7.2. ISSN 1447-9315.2022. Pag 41-50.
Avdeev S.N. Acute exacerbation of chronic obstructive pulmonary disease. Pulmonologiya. 2013;(3):5-19.
Albertson T. E. et al. The pharmacological management of asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS) //Expert Opinion on Pharmacotherapy. – 2020. – Т. 21. – №. 2. – С. 213-231.
Thimraj T. A. et al. Oxidative Signaling in Chronic Obstructive Airway Diseases //Immunity and inflammation in health and disease. – Academic Press, 2018. – С. 79-98.
Kholjigitova M. Clinico-Immunological Parallels in Chronic Obstructive Bronchitis in Adolescents //J Pulm Respir Med. – 2014
. – Т. 4. – №. 206. – С. 2.