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Abstract
Obesity epidemic is increasing worldwide at an alarming rate in particular in African countries .Obesity among females more than males and its associated with age, sex and blood pressure(1) .Overweight refers to an excess amount of body weight that may come from muscles, bone, fat, and water, while obesity refers to an excess amount of body fat and leads to morbidity and mortality due to hypertension, dyslipidemia, type 2 diabetes ,coronary heart disease, stroke, gallbladder disease, osteoarthritis, sleep apnea, respiratory problems and cancers.(2 ). The objective of this study is to assess the association of Cholesterol, Triglyceride and Leptin hormone Levels among Sudanese Obese Subjects in Khartoum state – Sudan. A case-control study was conducted during the period from January 2017 to August 2018. This study including 130 obese Sudanese individual and 50 ages matched apparently healthy volunteer as control. Total cholesterol and TRG were measured by (Mindary BS 380, China) ELISA method was used to measure level of leptin hormone. Data were analyzed by s (IBM, SPSS) version 21. T.test for means and standard deviation, while Pearson’s correlation between study variables. Mean level of BMI, T. cholesterol, TRG and leptin hormone were significantly increase among obese subjects rather than other control group, P value (0.000, 0.000, 0.000) respectively .There was no significant difference in mean of study parameters of the obese group according to gender classification except leptin hormone was found significant increase among female group, P.value (0.005).The Correlation studies showed positive between BMI(T.CH,TRG,leptin) R.value( 0.352,0.373,0.452) P.value (0.034,0032,0.004) respectively. This study conclude, significant increase in the serum lipids, of total cholesterol, triglycerides and leptin in obese subjects compare with control group, Positive correlation was observed between BMI and total cholesterol ,triglyceride and leptin hormone.
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