Keywords
antipsixotiklar
litiy tuzlari,
shizofreniya,
bipolyar buzilish
How to Cite
Abstract
Ushbu maqolada neyroleptiklar (antipsixotik dorilar) va litiy tuzlarining zamonaviy farmakologik xususiyatlari, ularning markaziy nerv tizimiga ta’sir mexanizmlari, klinik qo‘llanilishi hamda xavfsizlik jihatlari keng yoritilgan. Neyroleptiklar asosan dopamin D2 retseptorlarini bloklash orqali psixotik simptomlarni kamaytiradi va shizofreniya, psixoz hamda maniakal holatlarni davolashda muhim ahamiyatga ega. Litiy tuzlari esa bipolyar affektiv buzilishda kayfiyatni barqarorlashtiruvchi vosita sifatida qo‘llanilib, maniya va depressiya fazalarining oldini olishda asosiy o‘rin tutadi. Maqolada ushbu dorilarning farmakodinamikasi, farmakokinetikasi, nojo‘ya ta’sirlari hamda klinik amaliyotdagi ahamiyati tahlil qilingan.
References
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