Abstract
Mazkur maqolada kallikrein-kinin tizimining proteinopatiyalar rivojlanishidagi o‘rni va ahamiyati o‘rganilgan. Ushbu tizimning asosiy komponentlari bo‘lgan kallikrein va kininlar yallig‘lanish, qon aylanishi va og‘riq mexanizmlarida muhim rol o‘ynaydi. Proteinopatiyalar oqibatida kallikrein-kinin tizimining buzilishi kasallikning patogeneziga sezilarli ta’sir ko‘rsatadi.
Tadqiqot natijalari tizimning klinik biomarker sifatidagi ahamiyatini namoyon qiladi.
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