Keywords
How to Cite
Abstract
.При наличии исходно низкой продукции IgM в раневой
поверхности больных с генерализацией инфекции концентрация данного
иммуноглобулина лишь нарастает, что, по-видимому, было связано с
особенностями проявления общего заболевания. При этом, в случаях отсутствия
генерализации инфекции и при условии благоприятного исхода заболевания
продукция IgM снижается.
References
1. Храмилин В.Н. Современные аспекты местного лечения хронических ран
нижних конечностей у больных сахарным диабетом. // Научно- практический
медицинский журнал ЭНЦ РАМН.2015;4:26-30.
2. Stone R.C. A bioengineered living cell construct activates an acute wound
healing response in venous leg ulcers. // Sci. Transl. Med.2017;9(371):eaaf8611.
3. Burden of venous leg ulcers in the United States. / J.B. Rice, U. Desai, A.K.
Cummings, et al. // J. Med. Econ. 2014;17:347-356.
4. Driscoll P. Wound prevalence and wound management, 2012–2020. 2013. //
Accessed on 14 September 2015. Available online: http://blog.mediligence.com/
2013/01/29/wound-prevalence-and-wound- management-2012-2020/
5. Garraud O., Hozzein W.N., Badr G. Wound healing: Time to look for intelligent,
“natural” immunological approaches? // BMC Immunol.2020;(18):23.
6. An economic evaluation of the impact, cost, and medicare policy implications
of chronic nonhealing wounds. / S.R. Nussbaum, M.J. Carter, C.E. Fife, et al. // Value
Health.2018;21:27–32.
7. The humanistic and economic burden of chronic wounds: A systematic review.
/ M. Olsson, K. Jarbrink, U. Divakar, et al. // Wound Repair. Regen.2019;27:114–125.
8. Skin wound healing process and new emerging technologies for skin wound care
and regeneration. / E.M. Tottoli, R. Dorati, I. Genta, et al. // Pharmaceutics.
2020;12:735.
9. Immune regulation of skin wound healing: Mechanisms and novel therapeutic
targets. / J. Larouche, S. Sheoran, K. Maruyama, et al. // Adv. Wound
Care.2018;7:209–231.
10.Khamdamova M.T., Akramova D. E. Genetic aspects of genital prolapse in
women of reproductive age // New day in medicine. Bukhara, 2023. - No. 5
(55). - Р. 638-643.
11.Khamdamova M.T., Teshaev Sh.Zh., Hikmatova M.F. Morphological
changes of the thymus and spleen in renal failure in rats and correction with
pomegranate seed oil // New day in medicine. Bukhara, 2024. - N. 3(65). - Р.
167-187.
12.Khamdamova M. T. The state of local immunity in background diseases of
the cervix // Eurasian journal of medical and natural sciences Innovative
Academy Research Support Center.Volume 3 Issue 1, January 2023 ISSN
2181-287X R.171-175.
13.Khamdamova M.T., Khasanova M.T. Various mechanisms of pathogenesis
of endometrial hyperplasia in postmenopausal women (literature review) //
New day in medicine. Bukhara. 2023. - No. 8 (58). - Р. 103-107.
14. Khamdamova M.T. Reproductive Health of Women Using CopperContaining Intrauterine Contraception // Eurasian Medical Research
Periodical Volume 28 January 2024, ISSN: 2795-7624
.www.geniusjournals.org P. 39-45.
15. Khamdamov I.B. Advantages Of Laparoscopic Hernioplasty in Obesity
Women of Fertile Age // Eurasian Medical Research Periodical Volume 28
January 2024, ISSN: 2795-7624 .www.geniusjournals.org P. 33-38.
16.Khamdamova M.T., Zhaloldinova M.M., Khamdamov I.B. The state of nitric
oxide in blood serum in patients with cutaneous leishmaniasis // New day in
medicine. Bukhara, 2023. - No. 5 (55). - Р. 638-643.
17. Khamdamova M.T., Zhaloldinova M.M., Khamdamov I.B. The value of
ceruloplasmin and copper in blood serum in women wearing coppercontaining intrauterine device // New day in medicine. Bukhara, 2023. - No.
6 (56). - Р. 2-7.
18.Khamdamova M. T. Bleeding when wearing intrauterine contraceptives and
their relationship with the nitric oxide system // American journal of pediatric
medicine and health sciences Volume 01, Issue 07, 2023 ISSN (E): Р. 2993-
2149. R.58-62
19.Khamdamova M.T. Reproductive Health of Women Using CopperContaining Intrauterine Contraception // Eurasian Medical Research
Periodical Volume 28 January 2024, ISSN: 2795-7624
.www.geniusjournals.org P. 39-45.
20. Khamdamov I.B. Advantages Of Laparoscopic Hernioplasty in Obesity
Women of Fertile Age // Eurasian Medical Research Periodical Volume 28
January 2024, ISSN: 2795-7624 .www.geniusjournals.org P. 33-38.
21. Mesenchymal stem cells for chronic wound healing: Current status of preclinical
and clinical studies. / Y.Z. Huang, M. Gou, L.C. Da, et al. // Tissue Eng. Part B.
Rev.2020;26:555–570.
22. Goldberg S.R., Diegelmann R.F. What makes wounds chronic. // Surg. Clin.
New Am.2020;100:681–693.
23. Matrix metalloproteinases (MMPs) and diabetic foot: Pathophysiological
findings and recent developments in their inhibitors of natural as well as synthetic
origin. In The Eye and Foot in Diabetes. / K. Kaur, A. Singh, S. Attri, et al. // Intech.
Open: London, UK, 2020.
24. Validation of matrix metalloproteinase-9 (MMP-9) as a novel target for the
treatment of diabetic foot ulcers in humans and discovery of a potent and selective
small-molecule MMP-9 inhibitor that accelerates healing. / T.T. Nguyen, D. Ding,
W.R. Wolter, et al. // J. Med. Chem. 2018;61:8825–8837.
25. High glucose activates ERK1/2 to stabilize AP1 and increase MMP9 expression
in diabetic foot ulcers. / J. Lang, C. Yang, L. Liu, et al. // Exp. Cell Res. 2021;112550