How to Cite
Abstract
Bolalarda siydik yo‘llari infeksiyalari (SYI) pediatriya amaliyotida keng tarqalgan infeksion kasalliklardan biri bo‘lib, uning qaytalanuvchi shakllari buyrak to‘qimasining shikastlanishi va surunkali buyrak kasalliklari rivojlanish xavfini oshiradi. So‘nggi yillarda olib borilgan molekulyar-genetik tadqiqotlar immun javob genlari polimorfizmlarining kasallikka moyillik, klinik kechish va davolash samaradorligiga sezilarli ta'sir ko‘rsatishini isbotlamoqda. Mazkur tezisda TLR2, TLR4, IL-6, IL-8, TNF-α va CXCR1 genlari polimorfizmlarining klinik amaliy ahamiyati hamda ularni shaxsiylashtirilgan tibbiyotda qo‘llash istiqbollari yoritilgan.
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