Abstract
Acute Kidney Injury (AKI) is a common clinical syndrome characterized by a rapid decline in kidney function, leading to disturbances in fluid, electrolyte, and acid-base balance. AKI is associated with increased morbidity, mortality, prolonged hospital stay, and higher healthcare costs. Early diagnosis and timely management are essential for improving patient outcomes. This study aims to evaluate the clinical features, risk factors, diagnostic approaches, and preventive strategies associated with acute kidney injury. Understanding the mechanisms and consequences of AKI may contribute to better treatment and prognosis in affected patients
References
1. Kellum J.A., Lameire N., Aspelin P., et al. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney International Supplements. 2012;2(1):1–138.
2. Hoste E.A.J., Bagshaw S.M., Bellomo R., et al. Epidemiology of Acute Kidney Injury in Critically Ill Patients. New England Journal of Medicine. 2015;373(2):147–158.
3. Lewington A.J.P., Cerdá J., Mehta R.L. Raising Awareness of Acute Kidney Injury: A Global Perspective of a Silent Killer. Kidney International. 2013;84(3):457–467.
4. Makris K., Spanou L. Acute Kidney Injury: Definition, Pathophysiology and Clinical Phenotypes. Clinical Biochemist Reviews. 2016;37(2):85–98.
5. Mehta R.L., Cerda J., Burdmann E.A., et al. International Society of Nephrology's 0by25 Initiative for Acute Kidney Injury. The Lancet. 2015;385(9987):2616–2643.