INNOVATIVE THERAPEUTIC STRATEGIES FOR MANAGING POST CASTRATION SYNDROME AFTER OVARIAN HYPERSTIMULATION

Authors

  • Soxiba Narkulova Samarkand State Medical University, Department of Obstetrics and Gynecology No. 3 Author
  • Zarina Xudoyberdiyeva Samarkand State Medical University, Department of Obstetrics and Gynecology No. 3 Author

Keywords:

hydration

Abstract

Post‑castration syndrome (PCS) can develop after oocyte retrieval and luteal phase; severe ovarian hyperstimulation syndrome (OHSS) manifests as ascites, electrolyte imbalance, ovarian enlargement, and systemic signs. Although PCS is relatively rare, complications can be life-threatening and compromise IVF outcomes.

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References

1. Lainas TG et al.: Outpatient GnRH antagonist for established PCS resolves hematologic and ascitic findings within 7 days pubmed.ncbi.nlm.nih.gov.

2. Orvieto et al.: GnRH agonist trigger + freeze-all eliminates OHSS risk in antagonist cycles with ≥18 follicles pubmed.ncbi.nlm.nih.gov.

3. Cochrane reviews/meta-analyses: Cabergoline prophylaxis reduces OHSS incidence via VEGF modulation en.wikipedia.org.

4. De Vos et al.: In vitro maturation offers safer ART for PCOS with similar success rates en.wikipedia.org.

5. Wu et al.: AI model (“ILETIA”) enhances timing precision in stimulation, reducing risk factors .

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Published

2025-06-09

How to Cite

INNOVATIVE THERAPEUTIC STRATEGIES FOR MANAGING POST CASTRATION SYNDROME AFTER OVARIAN HYPERSTIMULATION. (2025). MULTIDISCIPLINARY JOURNAL: FUNDAMENTAL RESEARCH SCIENTIFIC JOURNAL, 1(6), 46-48. https://universalpublishings.com/index.php/fundamental/article/view/12314