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Keywords

og‘iz mikrobiotasi, biofilm, disbioz, kariyes, periodontit, metagenomika, fluorid, parhez, profilaktika.

How to Cite

OG‘IZ BO‘SHLIG‘I MIKROBIOTASINING KARIYES VA PERIODONTAL KASALLIKLAR RIVOJLANISHIDAGI O‘RNI HAMDA PROFILAKTIK YONDASHUVLAR. (2026). FAN, TA’LIM, TEXNOLOGIYA VA ISHLAB CHIQARISH INTEGRATSIYASI ASOSIDA RIVOJLANISH ISTIQBOLLARI, 3(8), 15-19. https://universalpublishings.com/index.php/fan/article/view/20452

Abstract

Og‘iz bo‘shlig‘i mikrobiotasi yuzlab bakterial turlar, zamburug‘lar, viruslar va boshqa  mikroorganizmlardan tashkil topgan murakkab ekologik tizim bo‘lib, sog‘lom holatda  mezbon bilan funksional muvozanatda yashaydi. Kariyes va periodontal kasalliklar 
odatda bitta patogenning mavjudligi bilan emas, mahalliy ekologik sharoitlar ta’sirida  biofilm funksiyasi va tarkibining disbiotik siljishi bilan bog‘liq. 

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References

1. Babikow E., Ghaltakhchyan N., Livingston T., et al. Longitudinal microbiome changes in supragingival biofilm transcriptomes induced by orthodontics. JDR Clinical & Translational Research. 2024;9(3):265-276. doi:10.1177/23800844231199393.

2. Wang Y., et al. Oral microbiome alterations associated with early childhood caries highlight the importance of dysbiosis and community-level changes. 2019. PMID:31690590.

3. Ji S., et al. Characteristics of the salivary microbiota in periodontal diseases and potential roles of individual bacterial species to predict disease severity. Microbiology Spectrum. 2023. PMID:37191548.

4. Simpson A., et al. Periodontal treatment causes a longitudinal increase in the oral nitrite-producing microbiome and alters salivary nitrate/nitrite biology. 2024. PMID:39169836.

5. Ho T.E., et al. Construction of an early childhood caries risk prediction model based on the oral microbiome: a nested case-control study. BMC Oral Health. 2025. PMID:40474179.

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