Open Access · Peer Reviewed
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Keywords

Ischemic heart disease
coronary artery disease
myocardial ischemia
angina pectoris
myocardial infarction

How to Cite

ISCHEMIC HEART DISEASE: CLASSIFICATION, DIAGNOSIS, AND TREATMENT STRATEGIES. (2026). FAN, TA’LIM, TEXNOLOGIYA VA ISHLAB CHIQARISH INTEGRATSIYASI ASOSIDA RIVOJLANISH ISTIQBOLLARI, 3(6), 108-114. https://universalpublishings.com/index.php/fan/article/view/19664

Abstract

Ischemic heart disease (IHD) remains one of the leading causes of morbidity and mortality worldwide, posing a significant burden on healthcare systems and society. This review article examines the current classification, diagnostic approaches, and treatment strategies for ischemic heart disease. The study highlights the pathophysiological mechanisms underlying myocardial ischemia and discusses the major clinical forms of the disease, including stable angina, unstable angina, and myocardial infarction. Modern diagnostic methods such as electrocardiography, cardiac biomarkers, echocardiography, stress testing, coronary angiography, and advanced imaging techniques are reviewed. Furthermore, contemporary treatment strategies, including lifestyle modification, pharmacological therapy, percutaneous coronary intervention, and coronary artery bypass grafting, are analyzed. Early diagnosis and evidence-based management are essential for improving patient outcomes and reducing cardiovascular mortality. The article emphasizes the importance of a multidisciplinary approach in the prevention, diagnosis, and treatment of ischemic heart disease.

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References

1. Virani SS, Alonso A, Aparicio HJ, Benjamin EJ, Bittencourt MS, Callaway CW, et al. Heart Disease and Stroke Statistics—2024 Update: A Report From the American Heart Association. Circulation. 2024;149(8):e347–e913.

2. Libby P. The changing landscape of atherosclerosis. Nature. 2021;592(7855):524–533.

3. Knuuti J, Wijns W, Saraste A, Capodanno D, Barbato E, Funck-Brentano C, et al. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes. Eur Heart J. 2020;41(3):407–477.

4. Gulati M, Levy PD, Mukherjee D, Amsterdam E, Bhatt DL, Birtcher KK, et al. 2021 AHA/ACC Guideline for the Evaluation and Diagnosis of Chest Pain. Circulation. 2021;144(22):e368–e454.

5. Collet JP, Thiele H, Barbato E, Barthélémy O, Bauersachs J, Bhatt DL, et al. 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J. 2021;42(14):1289–1367.

6. Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J. 2018;39(2):119–177.

7. O'Gara PT, Kushner FG, Ascheim DD, Casey DE Jr, Chung MK, de Lemos JA, et al. ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction. Circulation. 2013;127(4):e362–e425.

8. Fihn SD, Blankenship JC, Alexander KP, Bittl JA, Byrne JG, Fletcher BJ, et al. 2014 ACC/AHA/AATS/PCNA/SCAI/STS Focused Update of the Guideline for the Diagnosis and Management of Patients with Stable Ischemic Heart Disease. Circulation. 2014;130(19):1749–1767.

9. Maron DJ, Hochman JS, Reynolds HR, Bangalore S, O’Brien SM, Boden WE, et al. Initial Invasive or Conservative Strategy for Stable Coronary Disease. N Engl J Med. 2020;382(15):1395–1407.

10. Yusuf S, Joseph P, Rangarajan S, Islam S, Mente A, Hystad P, et al. Modifiable risk factors, cardiovascular disease, and mortality in 155,722 individuals from 21 high-income, middle-income, and low-income countries (PURE Study). Lancet. 2020;395(10226):795–808.

11. Bhatt DL, Eagle KA, Ohman EM, Hirsch AT, Goto S, Mahoney EM, et al. Comparative determinants of 4-year cardiovascular event rates in stable outpatients at risk of or with atherothrombosis. JAMA. 2010;304(12):1350–1357.

12. Braunwald E. The war against heart failure: the Lancet lecture. Lancet. 2015;385(9970):812–824.

13. Timmis A, Townsend N, Gale CP, Torbica A, Lettino M, Petersen SE, et al. European Society of Cardiology: Cardiovascular Disease Statistics 2023. Eur Heart J. 2024;45(1):4–15.

14. Ambrose JA, Singh M. Pathophysiology of coronary artery disease leading to acute coronary syndromes. F1000Prime Rep. 2015;7:08.

15. Writing Committee Members, Lawton JS, Tamis-Holland JE, Bangalore S, Bates ER, Beckie TM, et al. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization. Circulation. 2022;145(3):e18–e114.

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