BUXORO HUDUDIDA YASHOVCHI TUG’MA YURAK NUQSONI BO’LGAN BOLALARDA MTR A2756G; RS1805087 GENOTIPLARI
Keywords:
Tug'ma yurak nuqsonlari, bolalar, MTR a2756g, rs1805087, gen polimorfizmi, genotipAbstract
Tug'ma yurak nuqsonlari (TYN) yosh bolalar nogironligining asosiy sabablaridan biri bo'lib, erta o'limga olib kelishi mumkin[1,3]. Tug'ma yurak nuqsonlari rivojlanishining patogenezida ijtimoiy, irsiy, tibbiy omillar, shuningdek, atrof-muhit omillarining o’rni muhimdir.
References
1. Association between MTR A2756G polymorphism and susceptibility to congenital heart disease: A meta-analysis Wanru Liu, Jing Wang, Lin-jiao Chen-Published: July 8,
2022 https://doi.org/10.1371/journal.pone.0270828.
2. Murphy R.P., Donoghue C., Nallen R.J. et al. Prospective evaluation of the risk conferred by factor V Leiden and thermolabile methylenetet- rahydrofolate reductase polymorphisms in preg- nancy // Arterioscler Thromb Vasc Biol. 2000. Vol. 20 (1).
P. 266-270].
3. Study on Environmental Causes and SNPs of MTHFR, MS and CBS Genes Related to Congenital Heart Disease Hui Shi 1, Shiwei Yang 2, Yan Liu 1, Peng
Huang 3, Ning Lin 1, Xiaoru Sun 1, Rongbin Yu 3, Yuanyuan Zhang 3, Yuming Qin 2, Lijuan Wang 1 PMC4452709 DOI: 10.1371/journal.pone.0128646]





