ПОКАЗАТЕЛИ ОКСИДАТИВНОГО СТРЕССА У БОЛЬНЫХ С АРТРОЗО АРТРИТАМИ РАЗНОГО ВОЗРАСТА
PDF
ZENODO

Keywords

остеоартроз, прооксидантная система, антиоксидантная система, окислительная модификация белков, свободнорадикальное окисление липидов, супероксиддисмутаза, каталаза, миелопероксидаза, параоксаназа.

How to Cite

ПОКАЗАТЕЛИ ОКСИДАТИВНОГО СТРЕССА У БОЛЬНЫХ С АРТРОЗО АРТРИТАМИ РАЗНОГО ВОЗРАСТА . (2025). "Conference on Universal Science Research 2023", 3(2), 18-22. https://universalpublishings.com/index.php/cusr/article/view/10413

Abstract

В работе проведено комплексное лабораторное обследование больных разных стадий остеоартроза коленного сустава. Выявлены закономерности метаболических расстройств у больных остеоартрозом в виде активации прооксидантной системы и угнетения ферментативного звена антиоксидантной защиты. Показано, что степень окислительного стресса четко коррелирует с тяжестью клинических проявлений остеоартроза. Выявлены наиболее клинически значимые для лабораторной диагностики данной патологии показатели крови, такие как алифатические альдегидные группы окисленных белков и активность параоксаназы.

PDF
ZENODO

References

1. Bobaev N. M. Osteoarthritis and osteoporosis bilan birga kelishida khavf omillaring hususiyatlari : a scientific publication / N. M. Bobaev, M. Z. Rizamukhamedova, S. M. Muammadieva // Infection, immunity and Pharmacology : a scientific and practical journal. - 2019. - N 3. - С. 9-14.

2. Dadabayeva N. A. The role of metabolic syndrome and adipocytokines in the pathogenesis of osteoarthritis / N. A. Dadabayeva, H. T. Mirakhmedova, N. A. Ramazanova. - Text : direct // Bulletin of the Tashkent Medical Academy. - 2023.- N 5. - С. 58-60.

3. Konkova O.A., Nazarenko S.A., Umerenkova S.A., Shapovalova O.N. Inflammatory theories of osteoarthritis: aging of the immune system as a trigger factor in the pathogenesis of osteoarthritis//Alley of Science. 2019. t.1. № 3 (30). С. 143-146.

4. Kravtsov V.I., Sivordova L.E., Polyakova Yu.V., Zavodovsky B.V. Lipid imbalance in patients with osteoarthritis and its role in the pathogenesis of the disease// In the book: Days of Rheumatology in St. Petersburg - 2017. Collection of abstracts of the Congress with international participation. Edited by V.I. Mazurov. 2017. pp. 121-123.

5. Khamdamov I.B. Improving tactical approaches in the treatment of hernias of the anterior abdominal wall in women of fertile age // New day in medicine. Bukhara, 2022.-№10(48)- pp. 338-342.

6. Khamdamov I.B. Morphofunctional features of the abdominal press in women of reproductive age // New day in medicine. Bukhara, 2022.-№3(41)- pp. 223-227.

7. Khamdamova M.T. Ultrasound features of three-dimensional echography in assessing the condition of the endometrium and uterine cavity in women of the first period of middle age using intrauterine contraceptives // Biology va tibbyot muammolari. - Samarkand, 2020. - No. 2 (118). - P.127-131.

8. Khamdamova M. T. Аnthropometric characteristics of the physical status of women in the first and second period of middle age // A new day in medicine. Tashkent, 2020. - № 1 (29). - C.98-100.

9. Khamdamova M.T., Zhaloldinova M.M., Khamdamov I.B. The state of nitric oxide in blood serum in patients with cutaneous leishmaniasis // New day in medicine. Bukhara, 2023. - No. 5 (55). - pp. 638-643.

10. Khamdamova M.T., Zhaloldinova M.M., Khamdamov I.B. The value of ceruloplasmin and copper in blood serum in women wearing copper-containing intrauterine device // New day in medicine. Bukhara, 2023. - No. 6 (56). - pp. 2-7. 11.Khamdamova M. T. Bleeding when wearing intrauterine contraceptives and their relationship with the nitric oxide system // American journal of pediatric medicine and health sciences Volume 01, Issue 07, 2023 ISSN (E): 2993-2149. Р.58-62

12. Khamdamova M. T. The state of local immunity in background diseases of the cervix // Eurasian journal of medical and natural sciences Innovative Academy Research Support Center.Volume 3 Issue 1, January 2023 ISSN 2181-287X Р.171-175.

13.Khamdamova M.T., Khasanova M.T. Various mechanisms of pathogenesis of endometrial hyperplasia in postmenopausal women (literature review) // New day in medicine. Bukhara. 2023. - No. 8 (58). - pp. 103-107.

14. Khamdamova M.T. Reproductive Health of Women Using Copper-Containing Intrauterine Contraception // Eurasian Medical Research Periodical Volume 28 January 2024, ISSN: 2795-7624 .www.geniusjournals.org P. 39-45.

15. Khamdamov I.B. Advantages Of Laparoscopic Hernioplasty in Obesity Women of Fertile Age // Eurasian Medical Research Periodical Volume 28 January 2024, ISSN: 2795-7624 .www.geniusjournals.org P. 33-38.

16. Khamdamova M. T., Khasanova M.T. Genetic mechanisms of development of endometrial hyperplastic processes in women in menopacteric age // American Journal of Medicine and Medical Sciences 2025.- №15(2): Р.372-375 DOI: 10.5923/j.ajmms. 20251502.22

17. Khamdamova M. T., Akramova D.E. The problem of pelvic organ prolapse in women in modern gynecology // American Journal of Medicine and Medical Sciences 2025, 15(2): 483-486 DOI: 10.5923/j.ajmms.20251502.47

18. Khamdamova M. T., Umidova Nigora Nabi kizi. Endometriosis and women's reproductive health // American Journal of Medicine and Medical Sciences 2025; 15(2): 407-410 DOI:10.5923/j.ajmms.20251502.28

19. Khamdamov B. Z. et al. The role and place laser photodynamic therapy in prevention postoperative complication at treatment of diabetic foot syndrome //Applied Sciences: challenges and solutions. – 2015. – С. 27-31.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.