THE CLINICAL SIGNIFICANCE OF HEART RATE VARIABILITY (HRV) IN CARDIOVASCULAR RISK PREDICTION

Authors

  • Nuralieva Dilbar Student of the Termez branch of the Tashkent medical academy

Keywords:

: heart rate variability, cardiovascular disease, autonomic nervous system, diagnosis, arrhythmia, myocardial infarction

Abstract

Heart Rate Variability (HRV) represents the physiological variation in time intervals between successive heartbeats and serves as a non-invasive indicator of autonomic nervous system activity. Decreased HRV has been strongly associated with an increased risk of cardiovascular events, including myocardial infarction, heart failure, and arrhythmias. This article explores the physiological basis of HRV, its measurement techniques (time-domain and frequency-domain analyses), and its clinical relevance in cardiovascular risk prediction. It further discusses the potential of HRV as a tool for early diagnosis and for developing personalized therapeutic strategies in cardiology.

References

1. Shaffer, F., & Ginsberg, J. P. (2017). An Overview of Heart Rate Variability Metrics and Norms. Frontiers in Public Health, 5, 258. https://doi.org/10.3389/fpubh.2017.00258

2. Thayer, J. F., Yamamoto, S. S., & Brosschot, J. F. (2010). The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors. International Journal of Cardiology, 141(2), 122–131. https://doi.org/10.1016/j.ijcard.2009.09.543

3. Tsuji, H., et al. (1996). Impact of reduced heart rate variability on risk for cardiac events: The Framingham Heart Study. Circulation, 94(11), 2850–2855. https://doi.org/10.1161/01.CIR.94.11.2850

4. Malik, M., et al. (1996). Heart rate variability: Standards of measurement, physiological interpretation, and clinical use. European Heart Journal, 17(3), 354–381. https://doi.org/10.1093/oxfordjournals.eurheartj.a014868

5. Sessa, F., Anna, V., Messina, G., Cibelli, G., Monda, V., Marsala, G., ... & Monda, M. (2018). Heart rate variability as predictive factor for sudden cardiac death. Aging, 10(2), 166–177. https://doi.org/10.18632/aging.101386

6. Singh, N., Moneghetti, K. J., Christle, J. W., Hadley, D., Froelicher, V., & Plews, D. (2018). Heart rate variability: An old metric with new meaning in the era of using mHealth technologies for health and performance. Frontiers in Physiology, 9, 1100. https://doi.org/10.3389/fphys.2018.01100

7. Billman, G. E. (2011). Heart rate variability–a historical perspective. Frontiers in Physiology, 2, 86. https://doi.org/10.3389/fphys.2011.00086

8. Goldberger, J. J., et al. (2019). Autonomic Nervous System Dysfunction in Cardiovascular Disease: JACC Focus Seminar. Journal of the American College of Cardiology, 73(10), 1189–1206. https://doi.org/10.1016/j.jacc.2018.11.059

Downloads

Published

2025-06-23

How to Cite

THE CLINICAL SIGNIFICANCE OF HEART RATE VARIABILITY (HRV) IN CARDIOVASCULAR RISK PREDICTION. (2025). ACUMEN: INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH, 2(6), 366-372. https://universalpublishings.com/index.php/aijmr/article/view/12821