THE HABITAT AND ECOLOGICAL NICHES OF STAPHYLOCOCCI: A  SCIENTIFIC REVIEW

Zakirov Sh.Yu; Samandarova Barno Sultanovna; Khudayberganova Kamola Tajibayevna; Sadullaev Otanaza Kodirovich; Zokirova Mohira Shokirbekovna

Authors

Zakirov Sh.Yu - PhD in Medicine, Associate Professor of the Department of Microbiology, Virology and Immunology, Urgench State Medical Institute, Urgench, Uzbekista
Samandarova Barno Sultanovna PhD in Biology, Associate Professor, Head of the Department of Microbiology, Virology and Immunology, Urgench State Medical Institute, Urgench, Uzbekistan
Khudayberganova Kamola Tajibayevna Assistant at the Department of Microbiology, Virology and Immunology, Urgench State Medical Institute, Urgench, Uzbekistan
Sadullaev Otanaza Kodirovich PhD in Medicine, Associate Professor of the Department of Microbiology, Virology and Immunology, Urgench State Medical Institute, Urgench, Uzbekistan
Zokirova Mohira Shokirbekovna 5th-year student of the Faculty of General Medicine, Urgench State Medical Institute, Urgench, Uzbekistan

Keywords:

Staphylococcus, ecological niches, habitats, microbiota, transmission, antibiotic resistance, reservoirs.

Abstract

In mammals, staphylococci physiologically colonize the skin, sebaceous and sweat glands, and the mucous
membranes of the nose, oropharynx, intestines, and urogenital tract [2,6,10,16]. Staphylococcus aureus permanently or transiently colonizes approximately 20-30% of the human population, predominantly in the nares and on the skin [1,10,14,16].

References

1. Haag, A. F., Fitzgerald, J. R., Penadés, J. R. (2019). Staphylococcus aureus in Animals. Microbiology spectrum, 7(3), 10.1128/microbiolspec.gpp3-0060-2019. ,https://doi.org/10.1128/microbiolspec.GPP3-0060-2019

2. Kosecka-Strojek, M., Buda, A., Międzobrodzki, J. (2018). Staphylococcal ,ecology and epidemiology. 11-24. https://doi.org/10.1016/B978-0-12-813547-

1.00002-9

3. Ahmad, F., Martuchelle, S. S., Andrade-Oliveira, A. L., Lanes Viana, V. E.,

Sousa, M. A. S. M., da Silveira, F. S., Nogueira-Diaz, M. A., Pereira, M. F., GiambiagideMarval, M., & Rossi, C. C. (2025). From Farm to Community: Dispersal of Potentially Pathogenic Staphylococcus and Mammaliicoccus Species and Antimicrobial Resistance Across Shared Environments. Current microbiology, 82(3), 104. https://doi.org/10.1007/s00284-025-04079-3

4. Silva, V.; Capelo, J.L.; Igrejas, G.; Poeta, P. (2021). Prevalence and Molecular Epidemiology of Staphylococcus aureus in European Wildlife. Proceedings of 1st International Electronic Conference on Biological Diversity, Ecology and Evolution. https://doi.org/10.3390/bdee2021-09489

5. Heaton, C. J., Gerbig, G. R., Sensius, L. D., Patel, V., & Smith, T. C. (2020). Staphylococcus aureus Epidemiology in Wildlife: A Systematic

Review. Antibiotics (Basel, Switzerland), 9(2), 89. https://doi.org/10.3390/antibiotics9020089

6. Bierowiec, K., Korzeniowska-Kowal, A., Wzorek, A., Rypuła, K., & Gamian, A. (2019). Prevalence of Staphylococcus Species Colonization in Healthy and Sick Cats. BioMed research international, 2019, 4360525. https://doi.org/10.1155/2019/4360525

7. Borisov, A. M., Golubkova, A. A., & Ruzhentsova, T. A. (2024). The priority of bacteria Staphylococcus spp. in the etiology of purulent septic infections through the prism of new diagnostic capabilities: A literature review. Epidemiology And Infectious Diseases, 29(4), 295-308. doi: 10.17816/EID632504

8. Nemeghaire, S., Argudín, M. A., Feßler, A. T., Hauschild, T., Schwarz, S., & Butaye, P. (2014). The ecological importance of the Staphylococcus sciuri species group as a reservoir for resistance and virulence genes. Veterinary microbiology, 171(3- 4), 342–356. https://doi.org/10.1016/j.vetmic.2014.02.005

9. Kastman, E. K., Kamelamela, N., Norville, J. W., Cosetta, C. M., Dutton, R. J., & Wolfe, B. E. (2016). Biotic Interactions Shape the Ecological

Distributions of Staphylococcus Species. mBio, 7(5), e01157-16. https://doi.org/10.1128/mBio.01157-16

10. Burian, M., Wolz, C., & Yazdi, A. S. (2022). Transcriptional adaptation of

staphylococci during colonization of the authentic human environment: An overview of transcriptomic changes and their relationship to physiological conditions. Frontiers in cellular and infection microbiology, 12, 1062329. https://doi.org/10.3389/fcimb.2022.1062329

11. Samandarova, B.S., & Zakirov, Sh.Yu. (2021). The prevalence of staphylococci in individuals with acne vulgaris and a study of their antibiotic sensitivity. In Materials of the Republican Scientific and Practical Conference "Current

Problems of Clinical and Sanitary Microbiology," 20-21.

12. Nagase, N., Sasaki, A., Yamashita, K., Shimizu, A., Wakita, Y., Kitai, S., & Kawano, J. (2002). Isolation and species distribution of staphylococci from animal and human skin. The Journal of veterinary medical science, 64(3), 245–250. https://doi.org/10.1292/jvms.64.245

13. Alqahtani, M. S. M., Shahin, G., Abdelalim, I. T. I., & Khalaf, S. M. H. (2025). Evaluation of ecological consequences on the global distribution of Staphylococcus aureus Rosenbach 1884 due to climate change, using Maxent modeling. Scientific reports, 15(1), 11457. https://doi.org/10.1038/s41598-025-87534-

2

14. Zakirov, Sh., Sadullaev, O., Samandarova, B., Allaberganova, & Z., Karimova, M. (2022). STUDY OF PATHOGENIC STAPHYLOCOCCUS (S.

AUREUS) CARRIAGE IN MEDICAL PERSONNEL OF SURGICAL DEPARTMENTS OF HEALTHCARE FACILITIES, MATERNITY HOSPITALS, AND INDICATORS OF ACQUIRED RESISTANCE TO VARIOUS ANTIMICROBIAL DRUGS. Journal of the Physician's Herald, 1 (1), 24-27. https://doi.org/10.38095/2181-466X-2020931-23-26

15. Røken, M., Iakhno, S., Haaland, A. H., Bjelland, A. M., & Wasteson, Y. (2024). The Home Environment Is a Reservoir for Methicillin-Resistant

Coagulase-Negative Staphylococci and Mammaliicocci. Antibiotics (Basel, Switzerland), 13(3), 279. https://doi.org/10.3390/antibiotics13030279

16. Gehrke, A. E., Giai, C., & Gómez, M. I. (2023). Staphylococcus aureus

Adaptation to the Skin in Health and Persistent/Recurrent Infections. Antibiotics

(Basel, Switzerland), 12(10), 1520. https://doi.org/10.3390/antibiotics12101520

17. Silva, V., Caniça, M., Capelo, J. L., Igrejas, G., & Poeta, P. (2020).

Diversity and genetic lineages of environmental staphylococci:

a surface water overview. FEMS microbiology ecology, 96(12), fiaa191.

https://doi.org/10.1093/femsec/fiaa191

18. Joglekar, P., Conlan, S., Lee-Lin, S. Q., Deming, C., Kashaf, S. S., NISC

Comparative Sequencing Program, Kong, H. H., & Segre, J. A. (2023). Integrated

genomic and functional analyses of human skin-associated Staphylococcus revealsextensive inter- and intra-species diversity. BioRxiv : the preprint server for biology,

2023.06.22.546190. https://doi.org/10.1101/2023.06.22.546190

19. Brauge, T., Bourdonnais, E., Trigueros, S., Cresson, P., Debuiche, S.,

Granier, S., & Midelet, G. (2024). Antimicrobial resistance and geographical

distribution of Staphylococcus sp. isolated from whiting (Merlangius merlangus) and

seawater in the English Channel and the North sea. Environmental pollution, 123434.

https://doi.org/10.1016/j.envpol.2024.123434

20. Belheouane, M., Vallier, M., Čepić, A., Chung, C. J., Ibrahim, S., & Baines,

J. F. (2020). Assessing similarities and disparities in the skin microbiota

between wild and laboratory populations of house mice. The ISME

journal, 14(10), 2367–2380. https://doi.org/10.1038/s41396-020-0690-7

21. Zakirov, Sh. Yu., Samandarova, B. S. (2021). The role of staphylococci in

individuals with acne vulgaris and the characteristics of their antibiotic sensitivity. In

Current Problems of Pharmacology and Pharmacotherapy: Proceedings

of the Republican Scientific and Practical Conference, 211-212.

22. Badawy, B., Elafify, M., Farag, A. M. M., Moustafa, S. M., Sayed-Ahmed,

M. Z., Moawad, A. A., Algammal, A. M., Ramadan, H., & Eltholth, M. (2022).

Ecological Distribution of Virulent Multidrug-Resistant Staphylococcus

aureus in Livestock, Environment, and Dairy Products. Antibiotics

(Basel, Switzerland), 11(11), 1651. https://doi.org/10.3390/antibiotics11111651

23. Youngblom, M. A., Imhoff, M. R., Smyth, L. M., Mohamed, M. A., Pepperell, C. S. (2023). Portrait of a generalist bacterium: pathoadaptation, metabolic specialization and extreme environments shape diversity of Staphylococcus saprophyticus. bioRxiv : the preprint server for biology, 2023.08.18.553882. https://doi.org/10.1101/2023.08.18.55388