In the realm of biotechnology, the ability to modify genetic information has revolutionized scientific research and medical advancements. With the emergence of vast databases containing genetic information, researchers now have powerful tools at their disposal to manipulate and engineer genomes. This article explores the utilization of genetic databases for the modification of genetic information, highlighting the significance of such databases in various fields including medicine, agriculture, and environmental conservation. Through a comprehensive literature review, methodologies employed in genetic modification are discussed, followed by suggestions for future research and implications. The article concludes by emphasizing the transformative potential of genetic databases in shaping the future of genetic engineering.
In the realm of biotechnology, the ability to modify genetic information has revolutionized scientific research and medical advancements. With the emergence of vast databases containing genetic information, researchers now have powerful tools at their disposal to manipulate and engineer genomes. This article explores the utilization of genetic databases for the modification of genetic information, highlighting the significance of such databases in various fields including medicine, agriculture, and environmental conservation. Through a comprehensive literature review, methodologies employed in genetic modification are discussed, followed by suggestions for future research and implications. The article concludes by emphasizing the transformative potential of genetic databases in shaping the future of genetic engineering.
Biotexnologiya sohasida genetik ma'lumotni o'zgartirish qobiliyati ilmiy tadqiqotlar va tibbiyot yutuqlarini inqilob qildi. Genetik ma'lumotlarni o'z ichiga olgan ulkan ma'lumotlar bazalarining paydo bo'lishi bilan tadqiqotchilar endi genomlarni manipulyatsiya qilish va muhandislik qilish uchun kuchli vositalarga ega. Ushbu maqola genetik ma'lumotlar bazasidan genetik ma'lumotlarni o'zgartirish uchun foydalanishni o'rganadi va bunday ma'lumotlar bazalarining tibbiyot, qishloq xo'jaligi va atrof-muhitni muhofaza qilish kabi turli sohalardagi ahamiyatini ta'kidlaydi. Keng qamrovli adabiyotlarni o'rganish orqali genetik modifikatsiyada qo'llaniladigan metodologiyalar muhokama qilinadi, so'ngra kelajakdagi tadqiqotlar va ta'sirlar uchun takliflar beriladi. Maqola gen muhandisligi kelajagini shakllantirishda genetik ma'lumotlar bazalarining transformatsion salohiyatini ta'kidlash bilan yakunlanadi.
В сфере биотехнологии возможность изменять генетическую информацию произвела революцию в научных исследованиях и достижениях медицины. С появлением обширных баз данных, содержащих генетическую информацию, исследователи получили в свое распоряжение мощные инструменты для манипулирования геномами и их конструирования. В этой статье исследуется использование генетических баз данных для модификации генетической информации, подчеркивая значение таких баз данных в различных областях, включая медицину, сельское хозяйство и охрану окружающей среды. Посредством всестороннего обзора литературы обсуждаются методологии, используемые в генетической модификации, а затем высказываются предложения по будущим исследованиям и последствиям. В заключение статьи подчеркивается преобразующий потенциал генетических баз данных в формировании будущего генной инженерии.
| № | Muallifning F.I.Sh. | Lavozimi | Tashkilot nomi |
|---|---|---|---|
| 1 | Numanjanov A.A. | Teacher | Andijan State University |
| № | Havola nomi |
|---|---|
| 1 | 1. Doudna, J. A., & Charpentier, E. (2014). The new frontier of genome engineering with CRISPR-Cas9. Science, 346(6213), 1258096. doi:10.1126/science.1258096 |
| 2 | 2. National Center for Biotechnology Information (NCBI). (n.d.). GenBank. Retrieved from https://www.ncbi.nlm.nih.gov/genbank/ |
| 3 | 3. The Cancer Genome Atlas (TCGA). (n.d.). Retrieved from https://www.cancer.gov/about-nci/organization/ccg/research/structural-genomics/tcga |
| 4 | 4. Gaj, T., Gersbach, C. A., & Barbas III, C. F. (2013). ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends in Biotechnology, 31(7), 397-405. doi:10.1016/j.tibtech.2013.04.004 |
| 5 | 5. Kanchiswamy, C. N., Maffei, M. E., Malnoy, M., & Velasco, R. (2015). CRISPR/Cas9 genome editing: A promising technology for the improvement of crops. Journal of Agricultural and Food Chemistry, 63(44), 1838-1852. doi:10.1021/acs.jafc.5b01583 |