ISSN 3060-4745 Open Access · Peer Reviewed
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Keywords

acute cholecystitis, early cholecystectomy, delayed cholecystectomy, Tokyo Guidelines,

How to Cite

ACUTE CHOLECYSTECTOMY: OPTIMAL TIMING OF SURGERY FOR ACUTE CHOLECYSTITIS (EARLY VS DELAYED OPERATION). (2026). ACUMEN: INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH, 3(9), 66-69. https://doi.org/10.66301/cfjd4v47

Abstract

The article provides a comparative analysis of outcomes between early  and delayed cholecystectomy for acute cholecystitis. Pathophysiological aspects of the  gallbladder inflammatory process determining surgical strategy across different time  windows  from  symptom  onset  are  reviewed.  Key  clinical  outcomes,  including  conversion  rates  to  open  surgery,  total  length  of  hospital  stay,  postoperative  complication rates (including bile duct injury), and cost-effectiveness, are analyzed.  Based on modern international guidelines (Tokyo Guidelines 2018), the advantages of  early  laparoscopic  cholecystectomy  as  the  gold  standard  of  treatment  are  substantiated.

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References

1. Mayumi T., Okamoto K., Takada T. et al. Tokyo Guidelines 2018: management bundles for acute cholecystitis. Journal of Hepato-Biliary-Pancreatic Sciences. 2018;25(1):96-100.

2. Gutt C. N., Encke J., Köninger J. et al. Acute cholecystitis: early versus delayed cholecystectomy, a multicenter randomized trial (ACDC trial). Annals of Surgery. 2013;258(3):385-393.

3. Roulin D., Saadi A., Di Mare L. et al. Early versus delayed laparoscopic cholecystectomy for acute cholecystitis: a randomized clinical trial. Annals of Surgery. 2016;264(5):717-722.

4. Ревишвили А. Ш., Федоров А. В., Сажин В. П. и др. Острый холецистит: клинические рекомендации по диагностике и лечению. Хирургия. Журнал им. Н.И. Пирогова. 2021;(12):5-15. (In Russ.)

5. Pisano M., Allievi N., Gurusamy K. et al. 2020 World Society of Emergency Surgery (WSES) guidelines for the management of acute calculus cholecystitis. World Journal of Emergency Surgery. 2020;15(1):61

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